Relationship between aspirin taking and gastroduodenal haemorrhage.
نویسندگان
چکیده
EDITORIAL COMMENT The causal relationship between aspirin and gastroduodenal haemorrhage is critically examined. Occult bleeding showed that as a group patients who had had a severe gastrointestinal bleed were not strikingly different from a group of people with normal digestive tracts. It seems likely that overt bleeding may be due to an idosyncratic response developing only in particular circumstances.
منابع مشابه
Prevalence and independent factors for gastroduodenal ulcers/erosions in asymptomatic patients taking low-dose aspirin and gastroprotective agents: the OITA-GF study.
BACKGROUND Although it is well known that aspirin causes gastroduodenal mucosal injury and that aspirin-induced gastroduodenal mucosal injury is often asymptomatic, the prevalence and independent factors for gastroduodenal mucosal injury have not been clarified in asymptomatic patients taking low-dose aspirin and gastroprotective agents. AIM To clarify the prevalence and independent factors f...
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BACKGROUND The mechanisms of aspirin induced gastroduodenal injury are not fully understood. Aspirin induces the release of reactive oxygen metabolites in animal models, which may contribute to mucosal injury. AIMS To investigate the effects of aspirin administered with placebo or antioxidants on gastric mucosal reactive oxygen metabolite release and gastroduodenal injury in human volunteers....
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ورودعنوان ژورنال:
- Gut
دوره 8 3 شماره
صفحات -
تاریخ انتشار 1967